This study findings has gone shocking for netizens as the discovery shows that certain drugs can reverse ageing during an animal test.
According to the scientist, leading the research study, says a drug can actually reverse aspects of ageing has been successfully trialled in animals.
Looking back at the research process, proponents have rejuvenated old mice to restore their stamina, coat of fur and even some organ function.
The team at Erasmus University Medical Center, in the Netherlands, are planning human trials for what they hope is a treatment for old age, says researchers in a BBC report.
Meanwhile, UK scientist said the findings were “impossible to dismiss”, but that unanswered questions remained.
According to the paper, the approach works by flushing out retired or “senescent” cells in the body that have stopped dividing.
The pool of researchers accumulated naturally with age and have a role in wound healing and stopping tumours.
But, while they appear to just sit there, senescent cells release chemicals that cause inflammation and have been implicated in ageing.
EUMC researchers has created a drug that selectively killed senescent cells by disrupting the chemical balance within them.
“I got very rebellious, people insisted I was crazy for trying and for the first three times they were right,” Dr. Peter de Keizer told the BBC.
On the fourth attempt he had something that seemed to work.
De Keizer tested it on mice that were just old (the equivalent of 90 in mouse years), those genetically programmed to age very rapidly and those aged by chemotherapy.
The full findings, published in the journal Cell, showed liver function was easily restored and the animals doubled the distance they would run in a wheel.
“We weren’t planning to look at their hair, but it was too obvious to miss,” De Keizer added.
The lead scientist also said there were a lot of “grey” results – things that seemed to improve in some mice but not all.
The drug was given three times a week and the experiments have been taking place for nearly a year.
The proponent also said there are no signs of side-effects but “mice don’t talk.”
However, it is thought the drug would have little to no effect on normal tissues.
When asked if this was a drug for ageing, Dr Keizer told the BBC News website: “I hope so, but the proof of the pudding is in the eating as you say.
“In terms of mouse work we are pretty much done, we could look at specific age-related diseases eg osteoporosis, but we should now prepare for clinical translation.”
Experts from UK has weighed on the findings, Dr Dusko Ilic, a stem cell scientist at King’s College London, said: “The finding is impossible to dismiss.
“[But] until more high-quality research is done, it is better to be reserved about these findings.
“Though, I would not be surprised if manufacturers try to capitalise on this and, in a few years, we could buy this peptide as a supplement over the counter.”
In the end, this interesting findings serve as milestone in the quest to combat ageing that normally endured by humans and other livings in the world.